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Article

Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study.

Journal of the National Cancer Institute - 4 Aug 2010

Amos Christopher I, Gorlov Ivan P, Dong Qiong, Wu Xifeng, Zhang Huifeng, Lu Emily Y, Scheet Paul, Greisinger Anthony J, Mills Gordon B, Spitz Margaret R

Abstract excerpt

Genome-wide association studies of white persons with lung cancer have identified a region of extensive linkage disequilibrium on chromosome 15q25.1 that appears to be associated with both risk for lung cancer and smoking dependence. Because studying African American persons, who exhibit lower levels of linkage disequilibrium in this region, may identify additional loci that are associated with lung cancer, we...

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Source

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Identifiers

PMID: 20554942
DOI: 10.1093/jnci/djq232
PMCID: PMC2914761

Genes

CHRNA5
CHRNA3
CHRNB4
PSMA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study.PMID 20554942Read ↗

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