Article
Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations.
Cancer research - 15 Jun 2009
Wu Chen, Hu Zhibin, Yu Dianke, Huang Liming, Jin Guangfu, Liang Jie, Guo Huan, Tan Wen, Zhang Mingfeng, Qian Ji, Lu Daru, Wu Tangchun, Lin Dongxin, Shen Hongbing
Abstract excerpt
Recent three genome-wide association studies have mapped a lung cancer susceptibility locus to chromosome 15q25 in Caucasians. However, the reported risk single nucleotide polymorphisms (SNPs) are extremely rare in Asians, arguing against any of these being causative variants. This study sought to identify other variants on 15q25 associated with lung cancer susceptibility in Chinese. Two-stage case-control...
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