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Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers

17 Jul 2022

Abstract excerpt

BACKGROUND: There is considerable evidence for the importance of the DNA methylome in metabolic health, for example, a robust methylation signature has been associated with body mass index (BMI). However, visceral fat (VF) mass accumulation is a greater risk factor for metabolic disease than BMI alone. In this study, we dissect the subcutaneous adipose tissue (SAT) methylome signature relevant to metabolic health...

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Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Epigenetics and DNA Methylation
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PMID: 35843982
DOI: 10.1186/s13073-022-01077-z

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