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Article

APOE and aging-related cognitive change in a longitudinal cohort of men.

Neurobiology of aging - 1 Aug 2016

Rantalainen Ville, Lahti Jari, Henriksson Markus, Kajantie Eero, Tienari Pentti, Eriksson Johan G, Raikkonen Katri

Abstract excerpt

We examined associations between APOE major isoforms, rs405509 promoter and rs440446 intron-1 polymorphisms, and nonpathologic cognitive aging. Men from the Helsinki Birth Cohort Study took the Finnish Defence Forces Basic Intellectual Ability Test twice, at age 20.1 (n = 404) and 67.6 years (n = 247). APOE major isoforms did not associate with cognitive ability. In the APOE major isoform-adjusted analyses, the...

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PMID: 27318143
DOI: 10.1016/j.neurobiolaging.2016.04.024

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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