Article
Differential effects of the APOE e4 allele on different domains of cognitive ability across the life-course.
European journal of human genetics : EJHG - 1 Jun 2016
Marioni Riccardo E, Campbell Archie, Scotland Generation, Hayward Caroline, Porteous David J, Deary Ian J
Abstract excerpt
The association between APOE genotype and cognitive function suggests a positive role for the e2 allele and a negative role for the e4 allele. Both alleles have relatively low frequencies in the general population; hence, meta-analyses have been based on many small, heterogeneous studies. Here, we report the APOE-cognition associations in the largest single analysis to date. APOE status and cognitive ability were...
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