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Article

Efficient biallelic mutation in porcine parthenotes using a CRISPR-Cas9 system.

Biochemical and biophysical research communications - 5 Aug 2016

Tao Li, Yang Mingyao, Wang Xiaodong, Zhang Zhenni, Wu Zhonghong, Tian Jianhui, An Lei, Wang Shumin

Abstract excerpt

The parthenotes represent ideal models mimicking the embryonic development and characterizing the function of maternal genomes as well as an alternative source of pluripotent cell lines. Besides, parthenogenetically activated (PA) embryos serve as a rapid assay system to maximize the efficiency of generating genetically modified pig CRISPR/Cas9 system, an efficient and multiplex gene editing tool, has been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27221047
DOI: 10.1016/j.bbrc.2016.05.100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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