Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted gene knock-in by CRISPR/Cas ribonucleoproteins in porcine zygotes.

Scientific reports - 14 Feb 2017

Park Ki-Eun, Powell Anne, Sandmaier Shelley E S, Kim Chan-Mi, Mileham Alan, Donovan David M, Telugu Bhanu P

Abstract excerpt

The domestic pig is an important "dual purpose" animal model for agricultural and biomedical applications. There is an emerging consensus in the biomedical community for the use of large animal models such as pigs to either serve as an alternative, or complement investigations from the mouse. However, the use of pig has not proven popular due to technical difficulties and time required in generating models with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Collagen Type I
Share to Gene Knock-In Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockout Techniques

Share to Gene Order

Share to Homologous Recombination

Share to Multiprotein Complexes

Share to Ribonucleoproteins

Share to Zygote

Source

Open in PubMed Open full text

Identifiers

PMID: 28195163
DOI: 10.1038/srep42458
PMCID: PMC5307959

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted gene knock-in by CRISPR/Cas ribonucleoproteins in porcine zygotes.PMID 28195163Read ↗

Efficient CRISPR/Cas9-mediated biallelic gene disruption and site-specific knockin after rapid selection of highly active sgRNAs in pigs.Semantic proximity Read ↗

GEEP Method: An Optimized Electroporation-Mediated Gene Editing Approach for Establishment of Knockout Pig Lines.Semantic proximity Read ↗

CRISPR/Cas Technology in Pig-to-Human Xenotransplantation ResearchSemantic proximity Read ↗

Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer.Semantic proximity Read ↗

Somatic cell reprogramming-free generation of genetically modified pigs.Semantic proximity Read ↗

Resources for genome editing in livestock: Cas9-expressing chickens and pigsSemantic proximity Read ↗

Efficient generation of gene-modified pigs via injection of zygote with Cas9/sgRNA.Semantic proximity Read ↗

Virus-Like Particles: The Next Frontier in Livestock Gene EditingSemantic proximity Read ↗

Genetically modified pigs for biomedical researchSemantic proximity Read ↗

Targeted Gene Editing in Porcine Germ Cells.Semantic proximity Read ↗

CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigsSemantic proximity Read ↗

Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.