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Article

Cohesin mutations in human cancer.

Biochimica et biophysica acta - 1 Aug 2016

Hill Victoria K, Kim Jung-Sik, Waldman Todd

Abstract excerpt

Cohesin is a highly-conserved protein complex that plays important roles in sister chromatid cohesion, chromatin structure, gene expression, and DNA repair. In humans, cohesin is a ubiquitously expressed, multi-subunit protein complex composed of core subunits SMC1A, SMC3, RAD21, STAG1/2 and regulatory subunits WAPL, PDS5A/B, CDCA5, NIPBL, and MAU2. Recent studies have demonstrated that genes encoding cohesin...

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Topics

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Share to Antigens, Nuclear
Share to Cell Cycle Proteins
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27207471
DOI: 10.1016/j.bbcan.2016.05.002
PMCID: PMC4980180

Genes

CDCA5
MAU2
NIPBL
RAD21
SMC3
STAG1
STAG2
WAPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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