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Article

Identification of genetic variants associated with susceptibility to West Nile virus neuroinvasive disease.

Genes and immunity - 1 Jul 2016

Long D, Deng X, Singh P, Loeb M, Lauring A S, Seielstad M

Abstract excerpt

West Nile virus (WNV) infection results in a diverse spectrum of outcomes, and host genetics are likely to influence susceptibility to neuroinvasive disease (West Nile neuroinvasive disease (WNND)). We performed whole-exome sequencing of 44 individuals with WNND and identified alleles associated with severe disease by variant filtration in cases, kernel association testing in cases and controls and...

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Identifiers

PMID: 27170560
DOI: 10.1038/gene.2016.21
PMCID: PMC5215919

Genes

HERC5
JARID2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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