Article
Identification of genetic variants associated with dengue or West Nile virus disease: a systematic review and meta-analysis.
BMC infectious diseases - 22 Jun 2018
Cahill Megan E, Conley Samantha, DeWan Andrew T, Montgomery Ruth R
Abstract excerpt
BACKGROUND: Dengue and West Nile viruses are highly cross-reactive and have numerous parallels in geography, potential vector host (Aedes family of mosquitoes), and initial symptoms of infection. While the vast majority (> 80%) of both dengue and West Nile virus infections result in asymptomatic infections, a minority of individuals experience symptomatic infection and an even smaller proportion develop severe...
Topics
- 2',5'-Oligoadenylate Synthetase
- Dengue
- Genetic Predisposition to Disease
- Histocompatibility Antigens Class I
- Humans
- Interferon-gamma
- Mannose-Binding Lectin
- Phosphoinositide Phospholipase C
- Receptors, CCR5
- West Nile Fever
