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Article

Genome-wide association study (GWAS) of human host factors influencing viral severity of herpes simplex virus type 2 (HSV-2).

Genes and immunity - 1 Feb 2019

Kleinstein Sarah E, Shea Patrick R, Allen Andrew S, Koelle David M, Wald Anna, Goldstein David B

Abstract excerpt

Herpes simplex virus type 2 (HSV-2) is an incurable viral infection with severity ranging from asymptomatic to frequent recurrences. The viral shedding rate has been shown as a reproducible HSV-2 severity end point that correlates with lesion rates. We used a genome-wide association study (GWAS) to investigate the role of common human genetic variation in HSV-2 severity. We performed a GWAS on 223 HSV-2-positive...

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PMID: 29535370
DOI: 10.1038/s41435-018-0013-4
PMCID: PMC6113125

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ABCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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