Article
Genetic variation in the HLA region is associated with susceptibility to herpes zoster.
Genes and immunity - 1 Jan 2000
Crosslin D R, Carrell D S, Burt A, Kim D S, Underwood J G, Hanna D S, Comstock B A, Baldwin E, de Andrade M, Kullo I J, Tromp G, Kuivaniemi H, Borthwick K M, McCarty C A, Peissig P L, Doheny K F, Pugh E, Kho A, Pacheco J, Hayes M G, Ritchie M D, Verma S S, Armstrong G, Stallings S, Denny J C, Carroll R J, Crawford D C, Crane P K, Mukherjee S, Bottinger E, Li R, Keating B, Mirel D B, Carlson C S, Harley J B, Larson E B, Jarvik G P
Abstract excerpt
Herpes zoster, commonly referred to as shingles, is caused by the varicella zoster virus (VZV). VZV initially manifests as chicken pox, most commonly in childhood, can remain asymptomatically latent in nerve tissues for many years and often re-emerges as shingles. Although reactivation may be related to immune suppression, aging and female sex, most inter-individual variability in re-emergence risk has not been...
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