Genetic variants and susceptibility to neurological complications following West Nile virus infection.

doi:10.1093/infdis/jir493

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Article

Genetic variants and susceptibility to neurological complications following West Nile virus infection.

The Journal of infectious diseases - 1 Oct 2011

Loeb Mark, Eskandarian Sasha, Rupp Mark, Fishman Neil, Gasink Leanne, Patterson Jan, Bramson Jonathan, Hudson Thomas J, Lemire Mathieu

Abstract excerpt

To determine genetic factors predisposing to neurological complications following West Nile virus infection, we analyzed a cohort of 560 neuroinvasive case patients and 950 control patients for 13 371 mostly nonsynonymous single-nucleotide polymorphisms (SNPs). The top 3 SNPs on the basis of statistical significance were also in genes of biological plausibility: rs2066786 in RFC1 (replication factor C1) (P = 1.88...

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Identifiers

PMID: 21881118
DOI: 10.1093/infdis/jir493
PMCID: PMC3203390

Genes

ANPEP
RFC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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