Article
Host genetic risk factors for West Nile virus infection and disease progression.
PloS one - 1 Jan 2011
Bigham Abigail W, Buckingham Kati J, Husain Sofia, Emond Mary J, Bofferding Kathryn M, Gildersleeve Heidi, Rutherford Ann, Astakhova Natalia M, Perelygin Andrey A, Busch Michael P, Murray Kristy O, Sejvar James J, Green Sharone, Kriesel John, Brinton Margo A, Bamshad Michael
Abstract excerpt
West Nile virus (WNV), a category B pathogen endemic in parts of Africa, Asia and Europe, emerged in North America in 1999, and spread rapidly across the continental U.S. Outcomes of infection with WNV range from asymptomatic to severe neuroinvasive disease manifested as encephalitis, paralysis, and/or death. Neuroinvasive WNV disease occurs in less than one percent of cases, and although host genetic factors are...
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