Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Precore/core region mutations of hepatitis B virus related to clinical severity.

World journal of gastroenterology - 7 May 2016

Kim Hong, Lee Seoung-Ae, Do Seung Yeon, Kim Bum-Joon

Abstract excerpt

Despite the availability of an effective vaccine, hepatitis B virus (HBV) infection remains a major health problem, with more than 350 million chronically infected people worldwide and over 1 million annual deaths due to cirrhosis and liver cancer. HBV mutations are primarily generated due both to a lack of proofreading capacity by HBV polymerase and to host immune pressure, which is a very important factor for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Hepatitis B, Chronic
Share to Hepatitis B Core Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepatitis B e Antigens

Share to Hepatitis B virus

Share to Liver Neoplasms

Share to Mutation

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 27158197
DOI: 10.3748/wjg.v22.i17.4287
PMCID: PMC4853686

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Precore/core region mutations of hepatitis B virus related to clinical severity.PMID 27158197Read ↗

Review on hepatitis B virus precore/core promoter mutations and their correlation with genotypes and liver disease severitySemantic proximity Read ↗

Naturally occurring precore/core region mutations of hepatitis B virus genotype C related to hepatocellular carcinoma.Semantic proximity Read ↗

Hepatitis B virus genetic variants: biological properties and clinical implicationsSemantic proximity Read ↗

Different precore/core mutations of hepatitis B interact with, limit, or favor liver fibrosis severity.Semantic proximity Read ↗

The Association Between Hepatitis B Virus Mutations and the Risk of Liver Disease and Hepatocellular Carcinoma.Semantic proximity Read ↗

Diagnosis of chronic hepatitis B and the implications of viral variants and mutations.Semantic proximity Read ↗

Subgenotype and genetic variability in the precore/core regions of hepatitis B virus in Korean patients with chronic liver disease.Semantic proximity Read ↗

Clinical significance of hepatitis B virus precore and core promoter variants in Korean patients with chronic hepatitis B.Semantic proximity Read ↗

Naturally occurring mutations in the HBV core N-terminal domain reduce viral replication and HBeAg levelsSemantic proximity Read ↗

A complete genomic analysis of hepatitis B virus isolated from 516 Chinese patients with different clinical manifestations.Semantic proximity Read ↗

Overview of hepatitis B viral replication and genetic variability.Semantic proximity Read ↗

Genetic variation of hepatitis B virus and its significance for pathogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.