Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Naturally occurring precore/core region mutations of hepatitis B virus genotype C related to hepatocellular carcinoma.

PloS one - 1 Jan 2012

Kim Dong-Won, Lee Seoung-Ae, Hwang Eung-Soo, Kook Yoon-Hoh, Kim Bum-Joon

Abstract excerpt

Previous studies have proved the presence of several distinct types of mutations in hepatitis B virus (HBV) infections, which are related to the progression of liver disease. However, few reports have detailed the mutation frequencies and mutation patterns in the precore/core (preC/C) region, which are based on the clinical status and HBeAg serostatus. Our aim in this study is to investigate the relationships...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Cluster Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Hepatitis B virus

Share to Liver Neoplasms

Share to Republic of Korea

Share to Statistics, Nonparametric

Share to Viral Core Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 23071796
DOI: 10.1371/journal.pone.0047372
PMCID: PMC3468518

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Naturally occurring precore/core region mutations of hepatitis B virus genotype C related to hepatocellular carcinoma.PMID 23071796Read ↗

Precore/core region mutations of hepatitis B virus related to clinical severity.Semantic proximity Read ↗

Genotypes and Hot Spot Mutations of Hepatitis B Virus in Northwest Chinese Population and Its Correlation with Diseases Progression.Semantic proximity Read ↗

Subgenotype and genetic variability in the precore/core regions of hepatitis B virus in Korean patients with chronic liver disease.Semantic proximity Read ↗

Comparative study of genotype B and C hepatitis B virus-induced chronic hepatitis in relation to the basic core promoter and precore mutations.Semantic proximity Read ↗

Clinical significance of hepatitis B virus precore and core promoter variants in Korean patients with chronic hepatitis B.Semantic proximity Read ↗

Characteristics of core promoter and precore stop codon mutants of hepatitis B virus in Vietnam.Semantic proximity Read ↗

The association between hepatitis B mutants and hepatocellular carcinoma: A meta-analysis.Semantic proximity Read ↗

Precore mutation of hepatitis B virus may contribute to hepatocellular carcinoma risk: evidence from an updated meta-analysis.Semantic proximity Read ↗

A complete genomic analysis of hepatitis B virus isolated from 516 Chinese patients with different clinical manifestations.Semantic proximity Read ↗

Hepatitis B virus genotypes and variants.Semantic proximity Read ↗

Role of hepatitis B virus base core and precore/core promoter mutations on hepatocellular carcinoma in untreated older genotype C Chinese patients.Semantic proximity Read ↗

Naturally occurring mutations in the HBV core N-terminal domain reduce viral replication and HBeAg levelsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.