Article
A complete genomic analysis of hepatitis B virus isolated from 516 Chinese patients with different clinical manifestations.
Journal of medical virology - 1 Oct 2013
Li Xiaodong, Liu Yan, Xu Zhihui, Wan Zhihong, Bai Siyu, Mao Panyong, Mao Yuanli, Xin Shaojie, Xu Dongping
Abstract excerpt
This study investigated features and clinical implications of HBV mutations in patients with different clinical manifestations. In total, 516 patients were enrolled in this study, including 131 patients with acute hepatitis B, 239 patients with chronic hepatitis B, and 146 patients with acute-on-chronic liver failure. HBV genotypes and mutations were analyzed by direct sequencing of complete viral genomes....
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