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Article

The Association Between Hepatitis B Virus Mutations and the Risk of Liver Disease and Hepatocellular Carcinoma.

Current molecular medicine - 1 Jan 2022

Akrami Hassan, Monjezi Mohammad Rafiee, Ilbeigi Shahrzad, Amiri Farshid, Fattahi Mohammad Reza

Abstract excerpt

Hepatitis B virus [HBV], the best-described hepadnavirus, is distributed all around the world and may lead to chronic and acute liver disease, cirrhosis, and hepatocellular carcinoma. Despite the advancement in treatment against HBV, an errorprone reverse transcriptase, which is required for HBV replication as well as host immune pressure, leads to constant evolution and emergence of genotypes, subgenotypes and...

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Identifiers

PMID: 34397330
DOI: 10.2174/1566524021666210816094412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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