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Article

Subgenotype and genetic variability in the precore/core regions of hepatitis B virus in Korean patients with chronic liver disease.

Intervirology - 1 Jan 2011

Lyoo Kwang Soo, Hong Sung Woo, Song Myeong Jun, Hur Wonhee, Choi Jung Eun, Piao Lian-Shu, Jang Jeong Won, Bae Si Hyun, Choi Jong Young, Park Jung Wha, Choi Sang Wook, Yoon Seung Kew

Abstract excerpt

OBJECTIVE: The aim of this study was to determine the prevalence of hepatitis B virus (HBV) subgenotypes, the spectrum of mutations in the precore/core region through phylogenetic analysis, and the relevance of viral characteristics in disease progression in Korean patients. METHODS: 133 patients with chronic HBV infection were enrolled. The precore and core region of HBV was amplified and sequenced. Phylogenetic...

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PMID: 21346309
DOI: 10.1159/000321359

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Source receipt: pubmed, retrieved 7 Sept 2026.

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