Article
Clinical significance of hepatitis B virus precore and core promoter variants in Korean patients with chronic hepatitis B.
Journal of clinical gastroenterology - 1 Jan 2015
Yim Sun Young, Um Soon Ho, Young Jung Jin, Kim Tae Hyung, Kim Jin Dong, Keum Bora, Seo Yeon Seok, Yim Hyung Joon, Jeen Yoon Tae, Lee Hong Sik, Chun Hoon Jai, Kim Chang Duck, Ryu Ho Sang
Abstract excerpt
BACKGROUND/AIM: We aimed to clarify the clinical significance of precore (preC)/core promoter (CP) variants of hepatitis B virus (HBV) in chronic hepatitis B (CHB) patients. METHODS: We assessed serum HBeAg, HBV DNA levels, alanine transferase (ALT) levels, and progression of liver fibrosis in 226 Korean CHB patients, presumed to be infected with genotype C HBV, to analyze HBV variants in the preC region (G1896A)...
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