Genetic variation of hepatitis B virus and its significance for pathogenesis.

doi:10.3748/wjg.v22.i1.126

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Article

Genetic variation of hepatitis B virus and its significance for pathogenesis.

World journal of gastroenterology - 7 Jan 2016

Zhang Zhen-Hua, Wu Chun-Chen, Chen Xin-Wen, Li Xu, Li Jun, Lu Meng-Ji

Abstract excerpt

Hepatitis B virus (HBV) has a worldwide distribution and is endemic in many populations. Due to its unique life cycle which requires an error-prone reverse transcriptase for replication, it constantly evolves, resulting in tremendous genetic variation in the form of genotypes, sub-genotypes, and...

Topics

Antineoplastic Agents
Genetic Variation
Genome, Viral
Genotype
Hepatitis B
Hepatitis B virus
Humans
Immunosuppression Therapy
Mutation
Recurrence
Viral Proteins
Virulence

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