Article
EigenGWAS: finding loci under selection through genome-wide association studies of eigenvectors in structured populations.
Heredity - 1 Jul 2016
Chen G-B, Lee S H, Zhu Z-X, Benyamin B, Robinson M R
Abstract excerpt
We develop a novel approach to identify regions of the genome underlying population genetic differentiation in any genetic data where the underlying population structure is unknown, or where the interest is assessing divergence along a gradient. By combining the statistical framework for genome-wide association studies (GWASs) with eigenvector decomposition (EigenGWAS), which is commonly used in population...
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