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Article

Control of population stratification by correlation-selected principal components.

Biometrics - 1 Sept 2011

Lee Seunggeun, Wright Fred A, Zou Fei

Abstract excerpt

In genome-wide association studies, population stratification is recognized as producing inflated type I error due to the inflation of test statistics. Principal component-based methods applied to genotypes provide information about population structure, and have been widely used to control for stratification. Here we explore the precise relationship between genotype principal components and inflation of...

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Identifiers

PMID: 21133882
DOI: 10.1111/j.1541-0420.2010.01520.x
PMCID: PMC3117098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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