Article
Investigation of the fine structure of European populations with applications to disease association studies.
European journal of human genetics : EJHG - 1 Dec 2008
Heath Simon C, Gut Ivo G, Brennan Paul, McKay James D, Bencko Vladimir, Fabianova Eleonora, Foretova Lenka, Georges Michael, Janout Vladimir, Kabesch Michael, Krokan Hans E, Elvestad Maiken B, Lissowska Jolanta, Mates Dana, Rudnai Peter, Skorpen Frank, Schreiber Stefan, Soria José M, Syvänen Ann-Christine, Meneton Pierre, Herçberg Serge, Galan Pilar, Szeszenia-Dabrowska Neonilia, Zaridze David, Génin Emmanuel, Cardon Lon R, Lathrop Mark
Abstract excerpt
An investigation into fine-scale European population structure was carried out using high-density genetic variation on nearly 6000 individuals originating from across Europe. The individuals were collected as control samples and were genotyped with more than 300 000 SNPs in genome-wide association studies using the Illumina Infinium platform. A major East-West gradient from Russian (Moscow) samples to Spanish...
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