Article
Deciphering signatures of natural selection via deep learning.
Briefings in bioinformatics - 20 Sept 2022
Qin Xinghu, Chiang Charleston W K, Gaggiotti Oscar E
Abstract excerpt
Identifying genomic regions influenced by natural selection provides fundamental insights into the genetic basis of local adaptation. However, it remains challenging to detect loci under complex spatially varying selection. We propose a deep learning-based framework, DeepGenomeScan, which can detect signatures of spatially varying selection. We demonstrate that DeepGenomeScan outperformed principal component...
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