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Article

Genetic and epigenetic determinants of B-cell lymphoma evolution.

Current opinion in hematology - 1 Jul 2016

Izzo Franco, Landau Dan A

Abstract excerpt

PURPOSE OF REVIEW: The success of targeted therapies fostered the development of increasingly specific and effective therapeutics for B-cell malignancies. However, cancer plasticity facilitates disease relapse, whereby intratumoral heterogeneity fuels tumor evolution into a more aggressive and resistant form. Understanding cancer heterogeneity and the evolutionary processes underlying disease relapse is key for...

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Share to Clonal Evolution
Share to Disease Progression
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genetic Heterogeneity

Share to Lymphoma, B-Cell

Share to Molecular Targeted Therapy

Share to Recurrence

Source

Identifiers

PMID: 27135978
DOI: 10.1097/MOH.0000000000000258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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