Article
Emerging trends and converging evidence in tumor evolution: A comprehensive review.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy - 1 May 2026
Jin Chenqi, Li Weiqi, Liu Boqiang, Cao Lu-Qi, Stefan Sven Marcel, Yuan Luoxi, Yu Xin, Shi Liang, Yu Hong
Abstract excerpt
BACKGROUND: Tumor evolution is a spatiotemporal dynamic process orchestrated by the interplay of genetic mutations, epigenetic reprogramming, and bidirectional microenvironmental interactions, which collectively generate the phenotypic diversity necessary for cancer progression, metastasis, and therapeutic resistance. Foundational models - linear, branched, neutral, and parallel evolution - provide complementary,...
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