Article
Novel insights into the disease dynamics of B-cell lymphomas in the Genomics Era.
The Journal of pathology - 1 Apr 2018
Chan Fong Chun, Lim Emilia, Kridel Robert, Steidl Christian
Abstract excerpt
High-throughput sequencing has significantly contributed to revealing the molecular underpinnings of B-cell lymphomagenesis and disease progression. It is now a widely accepted concept that the diversity of clinical responses to front-line therapy and the development of relapsed/refractory disease are in part explained by 'inter-patient' genetic heterogeneity measurable by individual sets of somatic gene...
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