Article
Rapid Detection of the GSTM3 A/B Polymorphism Using Real-time PCR with TaqMan(®) Probes.
Archives of medical research - 1 Feb 2016
Martínez-Treviño Denisse A, Moreno-Treviño María G, Salinas-Santander Mauricio, Wohn Luisa, Herrera-González Sarahí, Aguirre-Garza Marcelino, Rojas O Carolina, León-Cachón Rafael B R
Abstract excerpt
Glutathione S-transferases (GSTs) are a group of phase II detoxification enzymes, which catalyze the conjugation of glutathione (GSH) with carcinogens, among other xenobiotics. The GSTM3 gene is part of the GSTs gene family, and its polymorphism A/B has been associated with risk and protective effects of several cancers. This genetic variant is a deletion of 3 bp (AGG) in intron 6. Previous association studies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
