Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid detection of CYP2C18 genotypes by real-time fluorescence polymerase chain reaction.

The Journal of pharmacy and pharmacology - 1 Feb 2000

Mizugaki M, Hiratsuka M, Agatsuma Y, Matsubara Y, Fujii K, Kure S, Narisawa K

Abstract excerpt

In man, CYP2C19, a liver enzyme, plays an important role in the metabolism of several drugs. Mutation of the CYP2C19 gene results in a poor metaboliser phenotype. S-Mephenytoin hydroxylation genetic polymorphism is due to two mutations of the CYP2C19 gene, namely CYP2C19*2, located in exon 5, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Cytochrome P-450 Enzyme System
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Polymerase Chain Reaction

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 10714950
DOI: 10.1211/0022357001773850

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10714950-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid detection of CYP2C18 genotypes by real-time fluorescence polymerase chain reaction.PMID 10714950Read ↗

A rapid and simple detection of genetic defects responsible for the phenotypic polymorphism of cytochrome P450 2C19.Semantic proximity Read ↗

Rapid detection of CYP2C9*3 alleles by real-time fluorescence PCR based on SYBR Green.Semantic proximity Read ↗

An Extraction-Free Method for Rapid Detection of CYP2C19 * 2/3/17 Polymorphisms in One Tube using Melting Curve AnalysisSemantic proximity Read ↗

An extraction-free method for rapid detection of CYP2C19 * 2/3/17 polymorphisms in one tube using melting curve analysis.Semantic proximity Read ↗

Validation of a new fluorogenic real-time PCR assay for detection of CYP2C9 allelic variants and CYP2C9 allelic distribution in a German population.Semantic proximity Read ↗

Clinical application of a real-time polymerase chain reaction test for CYP2C19 genotyping based on genotype distribution in a healthy Korean population.Semantic proximity Read ↗

Detection of CYP2C19 alleles *1, *2 and *3 by multiplex polymerase chain reaction.Semantic proximity Read ↗

High throughput detection of drug-metabolizing enzyme polymorphisms by allele-specific fluorogenic 5' nuclease chain reaction assay.Semantic proximity Read ↗

Genetic variability of CYP2C19 in a Mexican population: contribution to the knowledge of the inheritance pattern of CYP2C19*17 to develop the ultrarapid metabolizer phenotype.Semantic proximity Read ↗

Development of a Polymerase Chain Reaction/Ligase Detection Reaction Assay for Detection of CYP2C19 Polymorphisms.Semantic proximity Read ↗

Genotyping and haplotyping of CYP2C19 functional alleles on thin-film biosensor chips.Semantic proximity Read ↗

A simple method for the detection of CYP2C9 polymorphisms: nested allele-specific multiplex polymerase chain reaction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.