Article
Detection of the FCGR3a polymorphism using a real-time polymerase chain reaction assay.
Cancer genetics - 1 Apr 2013
Burchard Paul R, Malhotra Saurabh, Kaur Prabhjot, Tsongalis Gregory J
Abstract excerpt
The fragment crystallizable (Fc) region of the immunoglobulin G, low affinity III A receptor (FCGR3a, also known as CD16) belongs to the Fc gamma receptor family (FCGR), which plays an important role in immunoinflammatory processes. It is a low affinity, transmembrane receptor that is mainly expressed in monocytes, natural killer cells, and macrophages. It has been implicated in various inflammatory conditions,...
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