Article
High prevalence of the GSTM3*A/B polymorphism in sub-Sarahan African populations.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jul 2010
Teixeira D, Vargens D, Príncipe A, Oliveira E, Amorim A, Prata M J, Suarez-Kurtz G
Abstract excerpt
A 3-bp insertion/deletion polymorphism in intron 6 of GSTM3 (rs1799735, GSTM3*A/*B) affects the activity of the phase 2 xenobiotic metabolizing enzyme GSTM3 and has been associated with increased cancer risk. The GSTM3*B allele is rare or absent in Southeast Asians, occurs in 5-20% of Europeans b...
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