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Article

Simultaneous genotyping of GSTT1 and GSTM1 null polymorphisms by melting curve analysis in presence of SYBR Green I.

The Journal of molecular diagnostics : JMD - 1 May 2010

Marín Fátima, García Nadia, Muñoz Xavier, Capellà Gabriel, González Carlos A, Agudo Antonio, Sala Núria

Abstract excerpt

Due to their ability to metabolize xenobiotics, glutathione S-transferases (GSTs) play an important role in cellular protection. GST family members mu (GSTM1) and theta (GSTT1) exhibit a common polymorphism that results in the complete deletion of the gene (null allele). Homozygous deletions, which result in the absence of the enzyme, are considered a risk factor for several diseases, including cancer. We report...

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Source

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Identifiers

PMID: 20203006
DOI: 10.2353/jmoldx.2010.090076
PMCID: PMC2860465

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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