Article
Analysis of GSTP1-1 polymorphism using real-time polymerase chain reaction.
Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2003
Ballerini Sabrina, Bellincampi Lorenza, Bernardini Sergio, Iori Roberta, Cortese Claudio, Federici Giorgio
Abstract excerpt
BACKGROUND: Glutathione transferases (GSTs) play an important role in the protection of cells from the products of oxidative stress as well as from several environmental carcinogens. The GSTP1-1 gene class is significantly overexpressed in many human tumors. Four allelic variants have been described for the GSTP1-1 gene (*A, *B, *C, *D) leading to different amino acid substitutions in position 105 and 114 of the...
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