Article
A novel Real Time PCR strategy to detect SOD3 SNP using LNA probes.
Mutation research - 2 Oct 2009
Brugè Francesca, Littarru Gian Paolo, Silvestrini Lucia, Mancuso Tommaso, Tiano Luca
Abstract excerpt
Extracellular superoxide dismutase (SOD3) is the primary enzymatic antioxidant defence of the vascular wall. The physiopathological role of SOD3 has been examined in vascular-related diseases, atherosclerosis, hypertension, diabetes, ischaemia-reperfusion injury, lung disease, various inflammatory conditions, and neurological diseases. An important single nucleotide polymorphism (SNP), nt.760 G>C of the SOD3 gene...
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