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Article

Additive genetic contribution to symptom dimensions in major depressive disorder.

Journal of abnormal psychology - 1 May 2016

Pearson Rahel, Palmer Rohan H C, Brick Leslie A, McGeary John E, Knopik Valerie S, Beevers Christopher G

Abstract excerpt

Major depressive disorder (MDD) is a phenotypically heterogeneous disorder with a complex genetic architecture. In this study, genomic-relatedness-matrix restricted maximum-likelihood analysis (GREML) was used to investigate the extent to which variance in depression symptoms/symptom dimensions can be explained by variation in common single nucleotide polymorphisms (SNPs) in a sample of individuals with MDD (N =...

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Source

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Identifiers

PMID: 27124715
DOI: 10.1037/abn0000161
PMCID: PMC4852390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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