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Article

Symptom dimensions of major depression in a large community-based cohort.

Psychological medicine - 1 Jan 2023

Wainberg Michael, Zhukovsky Peter, Hill Sean L, Felsky Daniel, Voineskos Aristotle, Kennedy Sidney, Hawco Colin, Tripathy Shreejoy J

Abstract excerpt

BACKGROUND: Our understanding of major depression is complicated by substantial heterogeneity in disease presentation, which can be disentangled by data-driven analyses of depressive symptom dimensions. We aimed to determine the clinical portrait of such symptom dimensions among individuals in the community. METHODS: This cross-sectional study consisted of 25 261 self-reported White UK Biobank participants with...

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Identifiers

PMID: 34008483
DOI: 10.1017/S0033291721001707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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