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Genetic factors and symptom dimensions associated with antidepressant treatment outcomes: clues for new potential therapeutic targets?

27 Aug 2024

Abstract excerpt

Treatment response and resistance in major depressive disorder (MDD) show a significant genetic component, but previous studies had limited power also due to MDD heterogeneity. This literature review focuses on the genetic factors associated with treatment outcomes in MDD, exploring their overlap with those associated with clinically relevant symptom dimensions. We searched PubMed for: (1) genome-wide association...

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PMID: 39191930
DOI: 10.1007/s00406-024-01873-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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