Article

Atypical energy-related symptoms define biologically distinct subtypes of major depressive disorder

2026-07-04

Abstract excerpt

<h4>ABSTRACT</h4> Major depressive disorder (MDD) is a complex psychiatric disorder, characterized by a range of mood, cognitive, and neurovegetative symptoms. Current diagnostic criteria treat opposite symptom directions as equivalent; weight gain or loss, and increased or decreased sleep, each count toward a single diagnosis. We defined three subgroups of individuals meeting criteria for MDD: AERS+ (hypersomni...

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Literature Corpus work: 0298d244-27ff-538c-9195-bed1a20210fd
DOI: 10.64898/2026.07.02.26357101

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