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Article

Loss of expression of BAP1 is very rare in non-small cell lung carcinoma.

Pathology - 1 Jun 2016

Andrici Juliana, Parkhill Thomas R, Jung Jason, Wardell Kathryn L, Verdonk Brandon, Singh Arjun, Sioson Loretta, Clarkson Adele, Watson Nicole, Sheen Amy, Farzin Mahtab, Toon Christopher W, Gill Anthony J

Abstract excerpt

Germline mutations of the BAP1 gene have been implicated in a cancer predisposition syndrome which includes mesothelioma, uveal melanoma, cutaneous melanocytic lesions, renal cell carcinoma, and possibly other malignancies. Double hit inactivation of BAP1 with subsequent loss of expression of the BAP1 protein also occurs in approximately 50% of mesotheliomas. The link between BAP1 mutation and lung cancer is yet...

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Source

Identifiers

PMID: 27114369
DOI: 10.1016/j.pathol.2016.03.005

Genes

BAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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