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Article

Somatic Mutation of BAP1 Can Lead to Expression Loss in Non-Small Cell Lung Carcinoma: Next Generation Sequencing and IHC Analysis in A Large Single Institute Cohort.

International journal of surgical pathology - 1 Aug 2022

Sun Tong, Wang Xi, Wang Minhua, Minerowicz Christine, Sanchez Harold, Laskin William, Cohen Paul, Zhong Minghao

Abstract excerpt

Introduction. As a tumor suppressor, germline and somatic inactivation of BRCA1 associated protein 1 gene (BAP1) is a common finding in mesothelioma, melanocytic tumors, clear cell renal cell carcinoma and several other epithelial, mesenchymal and neural tumors. Incidence of BAP1 genetic alterations and subsequent expression loss has not been well established in non-small cell lung carcinoma (NSCLC) by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34970936
DOI: 10.1177/10668969211070179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Somatic Mutation of BAP1 Can Lead to Expression Loss in Non-Small Cell Lung Carcinoma: Next Generation Sequencing and IHC Analysis in A Large Single Institute Cohort.PMID 34970936Read ↗

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