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Article

Tumours associated with BAP1 mutations.

Pathology - 1 Feb 2013

Murali Rajmohan, Wiesner Thomas, Scolyer Richard A

Abstract excerpt

BAP1 (BRCA1-Associated Protein 1) was initially identified as a protein that binds to BRCA1. BAP1 is a tumour suppressor that is believed to mediate its effects through chromatin modulation, transcriptional regulation, and possibly via the ubiquitin-proteasome system and the DNA damage response pathway. Germline mutations of BAP1 confer increased susceptibility for the development of several tumours, including...

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Source

Identifiers

PMID: 23277170
DOI: 10.1097/PAT.0b013e32835d0efb

Genes

BAP1
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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