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Article

Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer.

Cancer research - 15 Jan 2016

Ohar Jill A, Cheung Mitchell, Talarchek Jacqueline, Howard Suzanne E, Howard Timothy D, Hesdorffer Mary, Peng Hongzhuang, Rauscher Frank J, Testa Joseph R

Abstract excerpt

Heritable mutations in the BAP1 tumor suppressor gene predispose individuals to mesothelioma and other cancers. However, a large-scale assessment of germline BAP1 mutation incidence and associated clinical features in mesothelioma patients with a family history of cancer has not been reported. Therefore, we examined the germline BAP1 mutation status of 150 mesothelioma patients with a family history of cancer, 50...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26719535
DOI: 10.1158/0008-5472.CAN-15-0295
PMCID: PMC4715907

Genes

BAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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