Article
Epigenomic elements analyses for promoters identify ESRRG as a new susceptibility gene for obesity-related traits.
International journal of obesity (2005) - 1 Jul 2016
Dong S-S, Guo Y, Zhu D-L, Chen X-F, Wu X-M, Shen H, Chen X-D, Tan L-J, Tian Q, Deng H-W, Yang T-L
Abstract excerpt
OBJECTIVES: With ENCODE epigenomic data and results from published genome-wide association studies (GWASs), we aimed to find regulatory signatures of obesity genes and discover novel susceptibility genes. METHODS: Obesity genes were obtained from public GWAS databases and their promoters were annotated based on the regulatory element information. Significantly enriched or depleted epigenomic elements in the...
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