Article
Detecting primary drug-resistant mutations in Korean HIV patients using ultradeep pyrosequencing.
Journal of virological methods - 1 Aug 2016
Cho Min-Chul, Park Chang-Wook, Park Borae G, Oh Heung-Bum, Choi Sang-Ho, Choi Sung-Eun, Cho Nam-Sun
Abstract excerpt
HIV primary resistance, drug resistance in treatment-naïve patients, is an emerging public health issue. The prevalence of HIV primary resistance mutations down to the level of 1% minor variants was investigated using ultradeep pyrosequencing (UDPS) in HIV-positive Korean blood donors and in treatment naïve chronic patients for the comparison. The entire pol region was sequenced from 25 HIV-positive blood donors,...
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