Article
Low-cost ultra-wide genotyping using Roche/454 pyrosequencing for surveillance of HIV drug resistance.
PloS one - 1 Jan 2012
Dudley Dawn M, Chin Emily N, Bimber Benjamin N, Sanabani Sabri S, Tarosso Leandro F, Costa Priscilla R, Sauer Mariana M, Kallas Esper G, O'Connor David H
Abstract excerpt
BACKGROUND: Great efforts have been made to increase accessibility of HIV antiretroviral therapy (ART) in low and middle-income countries. The threat of wide-scale emergence of drug resistance could severely hamper ART scale-up efforts. Population-based surveillance of transmitted HIV drug resistance ensures the use of appropriate first-line regimens to maximize efficacy of ART programs where drug options are...
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