Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of hepatitis B virus drug-resistant mutant haplotypes by ultra-deep pyrosequencing.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Oct 2012

Ko S-Y, Oh H-B, Park C-W, Lee H C, Lee J-E

Abstract excerpt

Direct sequencing and reverse hybridization are currently the main methods for detecting drug-resistance mutations of hepatitis B virus (HBV). However, these methods do not enable haplotype analysis so they cannot be used to determine whether the mutations are co-located on the same viral genome. This limits the accurate identification of viral mutants that are resistant to drugs with a high genetic barrier. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanine

Share to Hepatitis B

Share to Hepatitis B virus

Share to High-Throughput Nucleotide Sequencing

Share to Lamivudine

Share to Reproducibility of Results

Source

Identifiers

PMID: 22757653
DOI: 10.1111/j.1469-0691.2012.03951.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of hepatitis B virus drug-resistant mutant haplotypes by ultra-deep pyrosequencing.PMID 22757653Read ↗

Ultra-deep pyrosequencing of hepatitis B virus quasispecies from nucleoside and nucleotide reverse-transcriptase inhibitor (NRTI)-treated patients and NRTI-naive patients.Semantic proximity Read ↗

Use of massively parallel ultradeep pyrosequencing to characterize the genetic diversity of hepatitis B virus in drug-resistant and drug-naive patients and to detect minor variants in reverse transcriptase and hepatitis B S antigen.Semantic proximity Read ↗

Pyrosequencing method for sensitive detection of HBV drug resistance mutations.Semantic proximity Read ↗

Characterization of the dynamics of hepatitis B virus resistance to adefovir by ultra-deep pyrosequencing.Semantic proximity Read ↗

Analysis of potential antiviral resistance mutation profiles within the HBV reverse transcriptase in untreated chronic hepatitis B patients using an ultra-deep pyrosequencing method.Semantic proximity Read ↗

Analysis of Hepatitis C Virus Intrahost Diversity across the Coding Region by Ultradeep PyrosequencingSemantic proximity Read ↗

A deep-sequencing method detects drug-resistant mutations in the hepatitis B virus in Indonesians.Semantic proximity Read ↗

Dynamics of Genotypic Mutations of the Hepatitis B Virus Associated With Long-Term Entecavir Treatment Determined With Ultradeep Pyrosequencing: A Retrospective Observational Study.Semantic proximity Read ↗

Ultra-Deep Pyrosequencing Detects Conserved Genomic Sites and Quantifies Linkage of Drug-Resistant Amino Acid Changes in the Hepatitis B Virus GenomeSemantic proximity Read ↗

Detecting primary drug-resistant mutations in Korean HIV patients using ultradeep pyrosequencing.Semantic proximity Read ↗

Analysis of hepatitis B virus genotyping and drug resistance gene mutations based on massively parallel sequencing.Semantic proximity Read ↗

Amplification and pyrosequencing of near-full-length hepatitis C virus for typing and monitoring antiviral resistant strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.