Article
A Sensitivity and Consistency Comparison Between Next-Generation Sequencing and Sanger Sequencing in HIV-1 Pretreatment Drug Resistance Testing.
Viruses - 31 Oct 2024
Zhou Ying, Ouyang Fei, Liu Xiaoyan, Lu Jing, Hu Haiyang, Sun Qi, Yang Haitao
Abstract excerpt
Next-generation sequencing (NGS) for HIV drug resistance (DR) testing has an increasing number of applications for the detection of low-abundance drug-resistant variants (LA-DRVs) in regard to its features as a quasi-species. However, there is less information on its detection performance in DR detection with NGS. To determine the feasibility of using NGS technology in LA-DRV detection for HIV-1 pretreatment drug...
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