Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout.

Rheumatology (Oxford, England) - 1 Aug 2016

Rasheed Humaira, Phipps-Green Amanda J, Topless Ruth, Smith Malcolm D, Hill Catherine, Lester Susan, Rischmueller Maureen, Janssen Matthijs, Jansen Timothy L, Joosten Leo A, Radstake Timothy R, Riches Philip L, Tausche Anne-Kathrin, Lioté Frederic, So Alexander, van Rij Andre, Jones Gregory T, McCormick Sally P, Harrison Andrew A, Stamp Lisa K, Dalbeth Nicola, Merriman Tony R

Abstract excerpt

OBJECTIVE: Gout is associated with dyslipidaemia. Association of the apolipoprotein A1-C3-A4 gene cluster with gout has previously been reported in a small study. To investigate a possible causal role for this locus in gout, we tested the association of genetic variants from APOA1 (rs670) and APOC3 (rs5128) with gout. METHODS: We studied data for 2452 controls and 2690 clinically ascertained gout cases of...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-I
Share to Apolipoprotein C-III
Share to Apolipoproteins C
Share to Case-Control Studies
Share to Gout
Share to Multigene Family
Share to Uric Acid
Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 27094595
DOI: 10.1093/rheumatology/kew057
PMCID: PMC5854033

Genes

APOA1
APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout.PMID 27094595Read ↗

Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Māori and Pacific Men.Semantic proximity Read ↗

Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout.Semantic proximity Read ↗

The renal urate transporter SLC17A1 locus: confirmation of association with gout.Semantic proximity Read ↗

Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout.Semantic proximity Read ↗

Aotearoa New Zealand Māori and Pacific Population-amplified Gout Risk Variants: CLNK Is a Separate Risk Gene at the SLC2A9 Locus.Semantic proximity Read ↗

A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Māori, case and control sample sets.Semantic proximity Read ↗

Twenty-eight loci that influence serum urate levels: analysis of association with gout.Semantic proximity Read ↗

The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets.Semantic proximity Read ↗

Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects.Semantic proximity Read ↗

The association between the polymorphism rs2231142 in the ABCG2 gene and gout risk: a meta-analysis.Semantic proximity Read ↗

The SLC2A9 nonsynonymous Arg265His variant and gout: evidence for a population-specific effect on severity.Semantic proximity Read ↗

Association analysis of the beta-3 adrenergic receptor Trp64Arg (rs4994) polymorphism with urate and gout.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.