Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Twenty-eight loci that influence serum urate levels: analysis of association with gout.

Annals of the rheumatic diseases - 1 Jan 2016

Phipps-Green A J, Merriman M E, Topless R, Altaf S, Montgomery G W, Franklin C, Jones G T, van Rij A M, White D, Stamp L K, Dalbeth N, Merriman T R

Abstract excerpt

OBJECTIVES: Twenty-eight genetic loci are associated with serum urate levels in Europeans. Evidence for association with gout at most loci is absent, equivocal or not replicated. Our aim was to test the loci for association with gout meeting the American College of Rheumatology gout classification criteria in New Zealand European and Polynesian case-control sample sets. METHODS: 648 European cases and 1550...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AMP-Activated Protein Kinases
Share to Basic-Leucine Zipper Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Monocarboxylic Acid Transporters

Share to Organic Anion Transporters, Sodium-Independent

Share to Receptor, IGF Type 1

Share to Receptors, Somatomedin

Share to Uric Acid

Source

Identifiers

PMID: 25187157
DOI: 10.1136/annrheumdis-2014-205877

Genes

HLF
MAF
PDZK1
GCKR
INHBC
PRKAG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Twenty-eight loci that influence serum urate levels: analysis of association with gout.PMID 25187157Read ↗

Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk FactorsSemantic proximity Read ↗

The genetic basis of urate control and gout: Insights into molecular pathogenesis from follow-up study of genome-wide association study loci.Semantic proximity Read ↗

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.Semantic proximity Read ↗

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levelsSemantic proximity Read ↗

Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects.Semantic proximity Read ↗

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.Semantic proximity Read ↗

Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout.Semantic proximity Read ↗

Novel Genetic Variants Associated with Gout Identified Through a Genome-Wide Study in the UK Biobank (N = 150,542)Semantic proximity Read ↗

The Epidemiology and Genetics of Hyperuricemia and Gout across Major Racial Groups: A Literature Review and Population Genetics Secondary Database AnalysisSemantic proximity Read ↗

The Epidemiology and Genetics of Hyperuricemia and Gout Across Major Racial Groups: A literature Review and Population Genetics Secondary Data AnalysisSemantic proximity Read ↗

The renal urate transporter SLC17A1 locus: confirmation of association with gout.Semantic proximity Read ↗

An update on the genetics of hyperuricaemia and gout.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.